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About the Role

We're hiring a Staff Software Engineer to provide technical leadership across our engineering team as we continue to scale the platform behind Tamarind. You'll work closely with the CTO to shape technical direction while remaining deeply involved in execution. This is a hands-on technical leadership role focused on architecture, infrastructure, product development, code reviews, technical mentorship, and engineering best practices.

Responsibilities

Partner with the CTO on architecture, technical planning, and major engineering initiatives
Provide technical guidance across a team of 7-8 engineers
Lead design reviews and architectural discussions
Help engineers navigate complex technical challenges
Contribute directly to the codebase across infrastructure, backend services, APIs, and product development
Review code and provide feedback on implementation approaches
Identify opportunities to improve reliability, scalability, performance, and developer productivity
Support technical decision-making across new products and platform capabilities
Work closely with customers and internal stakeholders to understand requirements and translate them into practical solutions
Help establish engineering standards as the team continues to grow

Requirements

7+ years of software engineering experience
Experience serving as a senior technical contributor, staff engineer, principal engineer, or technical lead
Strong software architecture and distributed systems experience
Experience building and operating production infrastructure and cloud services
AWS experience (EC2, S3, DynamoDB, Docker, etc.)
Ability to mentor engineers and provide technical guidance across multiple projects
Strong communication skills and sound engineering judgment
Comfort operating in an early-stage startup environment

Skills

Software architecture
Distributed systems
Production infrastructure
Cloud services
AWS
EC2
S3
DynamoDB
Docker
Mentorship
Communication
Engineering judgment
DevOps
MLOps
Computational Biology

Location

San Francisco

Work Type

Onsite
Full-time

Experience Level

Staff Engineer
Technical Lead
Senior Technical Contributor
Principal Engineer

About the Company

Tamarind Bio enables scientists to access AI-powered drug discovery. Thousands of scientists from large pharma companies, top biotechs, and academic institutions use Tamarind to design protein drugs, improve industrial enzymes, and create cutting edge molecules. New AI models are quickly eclipsing physics-based tools in computational drug discovery. Scientists often struggle to fine-tune, deploy, and scale these models, leaving breakthroughs on the table. Tamarind provides a simple interface to the vast array of tools being released daily.
Our technology sits at the intersection of DevOps, MLOps, and Computational Biology. We support workloads ranging from large-scale ML inference and model deployment to workflow orchestration across research, infrastructure, and scientific computing environments.