Impress employers and recruiters.
Choose from hundreds of resume examples.

Impress employers and recruiters.
Choose from hundreds of resume examples.

Target Resume Now

About the Role

The post holder will act as a core Metabolomics specialist within the facility, taking independent technical ownership of high-end mass spectrometry platforms. They will work closely with researchers, taking the scientific lead on the metabolomics side of collaborative projects, ranging from experimental design through to final publication, both internally and with external collaborators.

Responsibilities

• Lead the development and validation of metabolomics mass spectrometry-based workflows, focusing on high-resolution platforms.
• Take the scientific and technical lead on the metabolomics component of collaborative projects.
• Operate and maintain liquid chromatography-mass spectrometry (LC-MS) systems (Thermo Orbitrap Excedion Pro, IQ-X, Waters TQ-XS).
• Establish, track, and review rigorous Quality Assurance (QA) and Quality Control (QC) metrics to ensure data accuracy and instrument stability.
• Perform advanced hardware troubleshooting and coordinate directly with service engineers.
• Train and collaborate with team members and researchers in MRC LMS research groups.
• Disseminate skills and expertise by assisting collaborators with experimental design, sample extraction protocols, and data interpretation.
• Develop and apply computational pipelines for complex data analysis (targeted and untargeted) and data visualization.
• Contribute to peer-reviewed publications and maintain accurate, complete records of analysis projects and methods.
• Present and communicate methods and results at facility meetings, workshops, and seminars.
• Oversee facility consumables infrastructure and track system utilization metrics.
• Comply with LMS safety practices and deliver safety training when appropriate.
• Undertake appropriate administration tasks.
• Attend relevant meetings.
• Undertake any necessary training and/or professional development.
• Undertake any other duties commensurate with the grade of the post as directed by the supervisor.

Requirements

• PhD in Analytical Sciences, Chemistry, Biochemistry or a related discipline, or equivalent professional experience.
• Hands-on experience with LC-MS and development of metabolomics workflows on high-resolution platforms (such as Thermo Orbitrap Excedion Pro/IQ-X).
• Hands-on experience with LC-triple quadrupole (such as Waters TQ-XS).
• Proficiency in the acquisition and processing of metabolomics data including the implementation of rigorous data QA and QC tracking.
• Ability to take the technical and scientific lead on the metabolomics component of collaborative research projects.
• Experience of working with biological and biomedical scientists in a collaborative fashion from experimental design to data interpretation.
• Previous experience of working with biological and clinical samples.
• Ability to communicate well, train scientists and disseminate skills and expertise.
• Track record of contribution to peer reviewed publications.
• Experience of developing targeted and untargeted metabolomics workflows, including stable isotope labeling incorporation experiments (Desirable).
• Hands-on experience with gas chromatography-mass spectrometry (GC-MS) (Desirable).
• Experience of programming or script utilization (e.g., using R) for data analysis and visualization (Desirable).
• Previous experience of managing other research staff (Desirable).
• Experience of MS-imaging approaches (Desirable).
• Willingness to work closely with colleagues and line manager to actively collaborate on complex biological questions and drive the scientific goals of researchers within the institute.
• Willingness to develop and implement advance state-of-the-art metabolomics workflows.
• High level of motivation and drive.
• Willingness to share knowledge and skills with other members of the team on a daily basis.
• Flexible attitude towards work.
• Discipline and regard for confidentiality and security at all times.
• Willingness to undertake any necessary training for the role.
• Willingness to travel both within the United Kingdom and abroad to conduct research and attend conferences.
• Must at all times carry out responsibilities with due regard to the MRC’s Code of Conduct, Equality and Diversity policy, Health and Safety policy, and Data Protection and Security policy.

Skills

• Metabolomics
• Lipidomics
• High-resolution mass spectrometry
• Orbitrap architectures
• Tribid installations
• Liquid chromatography-mass spectrometry (LC-MS)
• Quality Assurance (QA)
• Quality Control (QC)
• Hardware troubleshooting
• Computational pipelines for data analysis
• Data visualization
• Peer-reviewed publications
• Gas chromatography-mass spectrometry (GC-MS)
• Programming/script utilization (e.g., R)

Location

• Hammersmith, London

Work Type

• Full time

Experience Level

• Equivalent professional experience (alternative to PhD)
• Hands-on experience with LC-MS
• Hands-on experience with LC-triple quadrupole
• Proficiency in metabolomics data acquisition and processing
• Ability to lead metabolomics components of research projects
• Experience working with biological and biomedical scientists
• Previous experience with biological and clinical samples
• Ability to communicate and train scientists
• Track record of contribution to publications
• Experience developing metabolomics workflows (Desirable)
• Hands-on experience with GC-MS (Desirable)
• Experience with programming/scripting for data analysis (Desirable)
• Previous experience managing research staff (Desirable)
• Experience with MS-imaging approaches (Desirable)

Education Level

• PhD in Analytical Sciences, Chemistry, Biochemistry or a related discipline

Salary/Compensations

• £42,159 plus London Allowance £5,560 per annum

Benefits

• Defined benefit pension scheme
• Excellent holiday entitlement
• Access to employee shopping/travel discounts
• Salary sacrifice cycle to work scheme

About the Company

• The Laboratory of Medical Sciences (LMS) at Hammersmith Hospital is a core-funded MRC research institute with close links to Imperial College and the Imperial College Healthcare NHS Trust.
• The LMS focuses on basic science research into human diseases and its translation into clinical settings.
• The Metabolomics facility within the LMS focuses on advanced collaborative requirements in metabolomics and lipidomics, expanding its technology base with next-generation Orbitrap architectures and upcoming Tribid installations.
• UKRI is an organisation that brings together the seven disciplinary research councils, Research England and Innovate UK, building an independent organisation with a strong voice and vision ensuring the UK maintains its world-leading position in research and innovation.
• UKRI supports some of the world’s most exciting and challenging research projects, developing and operating remarkable scientific facilities.
• UKRI is pushing the frontiers of human knowledge through fundamental research and delivering benefits for UK society and the economy through world-class research, skills and business-led innovation.
• The MRC is a great place to work and progress your career, be it in scientific research or support functions.
• The MRC is a unique working environment where researchers are rewarded by world-class innovation and collaboration opportunities.
• The MRC is an excellent place to develop yourself further with a range of training & development opportunities, including professional registration with the Science Council.

Equal Opportunity

• The MRC values the diverse skills and experience of its employees and is committed to achieving equality of treatment for all.
• All individuals shall have equal opportunities for employment and advancement on the basis of their skills, aptitudes and abilities.
• The MRC is committed to the engagement and retention of the best possible talent and to creating an environment that encourages excellence in scientific research through good equalities and diversity leadership and management.
• UKRI believes that everyone has a right to be treated with dignity and respect, and to be provided with equal opportunities to thrive and succeed in an environment that enables them to do so.
• UKRI values diversity of thought and experience within inclusive groups, organisations and the wider community.
• As users of the disability confident scheme, any candidate who opts into the scheme and best meets the essential criteria, will be shortlisted for interview.
• We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
• UKRI seeks to ensure it creates and maintains a system of openness, fairness and inclusion – a collaborative, trusted environment, which is attractive to and accessible to everyone who is interested in developing their career with us.
• We welcome applications from all sections of the community irrespective of gender, race, ethnic or national origin, religion or belief, sexual orientation, disability or age.
• As "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy.